Substrate: PKC delta (Protein kinase C, delta)
Seq-ID: P09215 [Rattus norvegicus]
Download:fasta csv
Interaction Network(s): -
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein kinase binding,
metal ion binding,
calcium-independent protein kinase C activity,
ATP binding		 membrane fraction,
mitochondrion,
nucleus,
membrane		 intracellular signaling pathway,
positive regulation of MAPKKK cascade,
cellular response to glucose starvation,
response to amino acid stimulus,
response to hypoxia,
response to hydrogen peroxide,
response to organic cyclic substance,
aging,
response to drug,
response to heat,
response to glucose stimulus,
protein amino acid autophosphorylation,
collagen metabolic process,
aspartate transport,
response to mechanical stimulus,
cellular response to insulin stimulus,
induction of apoptosis,
positive regulation of glucose import,
positive regulation of MAP kinase activity,
response to ethanol
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 311 KPETPETVGIYQGFEKKTAVS SRC 15961393
LTP
0.15
 - -
0.40
 - medium
Y 311 KPETPETVGIYQGFEKKTAVS - 15541367
LTP
0.15
 - -
0.40
 - medium
Y 311 KPETPETVGIYQGFEKKTAVS SRC 14970215
LTP
0.15
 - -
0.40
 - medium
Y 311 KPETPETVGIYQGFEKKTAVS - 14715667
LTP
0.15
 - -
0.40
 - medium
Y 332 GNDIPDNNGTYGKIWEGSNRC - 15541367
LTP
0.67
 - -
0.33
 - medium
Y 332 GNDIPDNNGTYGKIWEGSNRC - 14715667
LTP
0.67
 - -
0.33
 - medium
T 505 ENIFGENRASTFCGTPDYIAP PDK-1 9748166
LTP
1.00
 - S_TKc
0.14
 - medium
T 505 ENIFGENRASTFCGTPDYIAP - 11381116
LTP
1.00
 - S_TKc
0.14
 - medium
T 505 ENIFGENRASTFCGTPDYIAP - 11350745
LTP
1.00
 - S_TKc
0.14
 - medium
Y 512 RASTFCGTPDYIAPEILQGLK - 11381116
LTP
1.00
 - S_TKc
0.11
 - medium
Y 512 RASTFCGTPDYIAPEILQGLK - 9326592
LTP
1.00
 - S_TKc
0.11
 - medium
Y 523 IAPEILQGLKYSFSVDWWSFG - 9326592
LTP
1.00
 - S_TKc
0.02
 - medium
S 643 PEFLNEKPQLSFSDKNLIDSM - 11381116
LTP
1.00
 - S_TK_X
0.37
 - medium
S 643 PEFLNEKPQLSFSDKNLIDSM - 11350745
LTP
1.00
 - S_TK_X
0.37
 - medium
S 662 SMDQTAFKGFSFVNPKYEQFL - 11381116
LTP
1.00
 - S_TK_X
0.20
 - medium
S 662 SMDQTAFKGFSFVNPKYEQFL - 16396499
HTP
1.00
 - S_TK_X
0.20
 - medium
S 662 SMDQTAFKGFSFVNPKYEQFL - 11350745
LTP
1.00
 - S_TK_X
0.20
 - medium

Substrate: PKC delta (Protein kinase C, delta)
Seq-ID: P28867 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein kinase C activity,
metal ion binding,
insulin receptor substrate binding,
ATP binding		 cytoplasm,
membrane		 protein amino acid phosphorylation,
negative regulation of insulin receptor signaling pathway,
negative regulation of peptidyl-tyrosine phosphorylation,
interleukin-10 production,
B cell proliferation,
immunoglobulin mediated immune response,
interleukin-12 production
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 43 KEALSTERGKTLVQKKPTMYP - 19144319
HTP
1.00
 - C2
0.44
 - low
Y 52 KTLVQKKPTMYPEWKTTFDAH Lyn 7575560
LTP
0.95
 - C2
0.32
 - low
Y 52 KTLVQKKPTMYPEWKTTFDAH - 15774464
LTP
0.95
 - C2
0.32
 - low
Y 64 EWKTTFDAHIYEGRVIQIVLM - 11812791
LTP
0.18
 - C2
0.10
 - low
T 141 MRSEEEAKFPTMNRRGAIKQA - 19144319
HTP
0.56
 - -
0.47
 - low
Y 155 RGAIKQAKIHYIKNHEFIATF SRC 10945993
LTP
0.37
 - -
0.11
 - low
Y 155 RGAIKQAKIHYIKNHEFIATF Lyn 7575560
LTP
0.37
 - -
0.11
 - low
Y 155 RGAIKQAKIHYIKNHEFIATF - 15774464
LTP
0.37
 - -
0.11
 - low
Y 187 EFVWGLNKQGYKCRQCNAAIH - 10945993
LTP
1.00
 - C1
0.03
 - low
Y 187 EFVWGLNKQGYKCRQCNAAIH - 15774464
LTP
1.00
 - C1
0.03
 - low
Y 187 EFVWGLNKQGYKCRQCNAAIH - 8824297
LTP
1.00
 - C1
0.03
 - low
Y 311 KLDTTESVGIYQGFEKKPEVS Lck 11381116
LTP
0.16
 - -
0.33
 - low
Y 311 KLDTTESVGIYQGFEKKPEVS - 19144319
HTP
0.16
 - -
0.33
 - low
Y 332 GSDILDNNGTYGKIWEGSTRC - 19144319
HTP
0.21
 SHC1 SH2 -
0.20
 - low
Y 565 FESIRVDTPHYPRWITKESKD Lyn 7575560
LTP
1.00
 - S_TKc
0.26
 - low
S 643 PEFLNEKPQLSFSDKNLIDSM PKC_delta 9305920
LTP
1.00
 - S_TK_X
0.36
 - low
S 662 SMDQEAFHGFSFVNPKFEQFL - 15731106
LTP
1.00
 - S_TK_X
0.16
 - low
S 662 SMDQEAFHGFSFVNPKFEQFL - 19144319
HTP
1.00
 - S_TK_X
0.16
 - low

Substrate: PKC delta (Protein kinase C, delta)
Seq-ID: P28867-2 [Mus musculus]
Download:fasta csv
Interaction Network(s):
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein kinase C activity,
metal ion binding,
insulin receptor substrate binding,
ATP binding		 cytoplasm,
membrane		 protein amino acid phosphorylation,
negative regulation of insulin receptor signaling pathway,
negative regulation of peptidyl-tyrosine phosphorylation,
interleukin-10 production,
B cell proliferation,
immunoglobulin mediated immune response,
interleukin-12 production
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 334 DILGEAGSHISLKLSFPSRAK - 19144319
HTP
0.00
 - -
0.26
 - medium

Substrate: PKC delta (Protein kinase C, delta)
Seq-ID: Q05655 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-62336   CDCP1_HUMAN
MINT-62340   SRC_HUMAN
MINT-1955124   ABL1_HUMAN
MINT-3973536   NCF1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
enzyme activator activity,
protein C-terminus binding,
metal ion binding,
insulin receptor substrate binding,
calcium-independent protein kinase C activity,
ATP binding,
enzyme binding		 plasma membrane,
cytosol,
nucleus,
endoplasmic reticulum		 protein stabilization,
protein amino acid phosphorylation,
senescence,
negative regulation of insulin receptor signaling pathway,
negative regulation of peptidyl-tyrosine phosphorylation,
signal transduction,
regulation of receptor activity,
negative regulation of protein binding
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 52 KTLVQKKPTMYPEWKSTFDAH - 15302935
HTP
0.95
 Lyn SH2 C2
0.32
 1YRK 62.01%
Y 64 EWKSTFDAHIYEGRVIQIVLM - 15302935
HTP
0.16
 - C2
0.09
 1YRK 44.54%
Y 155 RGAIKQAKIHYIKNHEFIATF - 15302935
HTP
0.41
 - -
0.12
 --
Y 187 DFVWGLNKQGYKCRQCNAAIH - 15302935
HTP
1.00
 - C1
0.04
 --
Y 187 DFVWGLNKQGYKCRQCNAAIH - 8824297
LTP
1.00
 - C1
0.04
 --
S 299 EALNQVTQRASRRSDSASSEP - 17603046
LTP
0.80
 - -
0.51
 --
S 302 NQVTQRASRRSDSASSEPVGI - 17603046
LTP
0.66
 - -
0.50
 --
S 304 VTQRASRRSDSASSEPVGIYQ - 17603046
LTP
0.74
 - -
0.46
 --
S 304 VTQRASRRSDSASSEPVGIYQ - 18088087
HTP
0.74
 - -
0.46
 --
Y 313 DSASSEPVGIYQGFEKKTGVA - 15302935
HTP
0.15
 - -
0.38
 --
Y 313 DSASSEPVGIYQGFEKKTGVA - 18083107
HTP
0.15
 - -
0.38
 --
Y 334 GEDMQDNSGTYGKIWEGSSKC - 18083107
HTP
0.16
 SHC1 SH2 -
0.34
 --
T 507 ENIFGESRASTFCGTPDYIAP PDK-1 9748166
LTP
1.00
 - S_TKc
0.14
 --
T 507 ENIFGESRASTFCGTPDYIAP - 15302935
HTP
1.00
 - S_TKc
0.14
 --
S 645 QEFLNEKARLSYSDKNLIDSM - 15302935
HTP
0.96
 - S_TK_X
0.29
 --
S 664 SMDQSAFAGFSFVNPKFEHLL - 15302935
HTP
0.99
 - S_TK_X
0.17
 --

Valid HTML 4.01 Transitional